- Apply by date - November 22nd @ 5pm
Title: Postdoc Researcher – Neurobiology
Department: RCSI Centre for Systems Medicine/SFI Future-Neuro Research Centre/Dept of Physiology and Medical Physics
Location: St. Stephen’s Green, Dublin
Term: 24 month fixed-term
Reporting to: Prof Jochen Prehn or nominee
Salary: In line with IUA Researcher’s Salary Scales
Applications: Email CV directly to Professor Jochen Prehn: jprehn@rcsi.ie by 5pm of Nov 22nd
Project Summary:
This trans-disciplinary project aims to approach a serious neurological problem through a solution bringing together synthetic biology, computer science, communication engineering, nanomedicine, bioengineering and material science.
This post-doctoral position will contribute to the PRIME project by experimentally evaluating the effect of tRNA-derived fragment and miRNA on neuronal function, excitability and epilepsy development. This work will employ molecular and cell biology techniques including primary cell culture, RNA silencing, single cell RNA sequencing, spatial transcriptomics, viral transduction, neuronal biochemistry, confocal imaging, image processing and data analysis.
The successful candidate will benefit from the multi-disciplinary expertise of the academic and industry partners of PRIME and FN with an aim to thoroughly characterise the function of tRNA-derived fragments, and identify novel disease biomarkers and innovative therapeutic targets for epilepsy and other hyperexcitation disorders.
Specific duties:
- Perform molecular biochemical and imaging studies to characterise the effect of tRNA-derived fragment and miRNA on neuronal function in epilepsy.
- Single RNA sequencing
- Contribute to successful interdisciplinary research by liaising closely with both experimental and computational researchers within the consortium.
- Keep excellent records, submit research for publication in peer reviewed journals, and contribute to internal and external reporting.
- Present research findings at international scientific conferences and at consortium meetings.
- Assist with teaching activities and supervision of graduate students and technical staff as required.
- Compliance with statutory legislation and implementation of College rules and requirements in furtherance of your own and general staff welfare and safety.
- Undertake programmes of training and development as required.
- The candidate must represent the best interests of the Department and RCSI at all times.
Person Specifications:
- Must have a Ph.D. (or submitted Ph.D. thesis) in Biochemistry, Molecular Biology, Cell Biology or similar discipline
- Research experience in primary cell culture and/or confocal imaging
- Demonstrated research publications and/or awards are of advantage
- Flexibility to work irregular hours on occasion
- Have a good knowledge of Health and Safety Legislation and its application in a laboratory environment.
- Excellent interpersonal skills, verbal and written communication skills.
Application Process
To apply for this post please forward your CV and cover letter to Professor Jochen Prehn: (jprehn@rcsi.ie) The deadline for applications is 5pm on the 22nd of November 2022. Informal queries can also be directed to Prof Prehn at the above email.